Crystal structure of EP300 HAT domain in complex with compound (+)-3
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Crystal structure of EP300 HAT domain in complex with compound (+)-3 Descriptor: Histone acetyltransferase p300, ZINC ION, [(6R)-6-(1H-indazol-4-ylmethyl)-1,4-oxazepan-4-yl]-[1-(4-methoxyphenyl)cyclopentyl]methanone Authors: Takahashi, M, Hanzawa, H. Deposit date: 2021-09-24 Release date: 2022-04-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Discovery of EP300/CBP histone acetyltransferase inhibitors through scaffold hopping of 1,4-oxazepane ring. Bioorg.Med.Chem.Lett., 66, 2022
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2021-09-24
