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Discovery of a Highly Potent and Broadly Effective EGFR and HER2 Exon 20 Insertion Mutant Inhibitor

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Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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Discovery of a Highly Potent and Broadly Effective EGFR and HER2 Exon 20 Insertion Mutant Inhibitor Descriptor: (4-fluorophenyl)methyl {2-[(1-methyl-1H-pyrazol-3-yl)amino]pyrimidin-4-yl}[3-(propanoylamino)phenyl]carbamate, Epidermal growth factor receptor Authors: Park, E, Eck, M.J. Deposit date: 2018-04-26 Release date: 2018-07-18 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.537 Å) Cite: Discovery of a Highly Potent and Broadly Effective Epidermal Growth Factor Receptor and HER2 Exon 20 Insertion Mutant Inhibitor. Angew. Chem. Int. Ed. Engl., 57, 2018

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2018-04-26
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