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Graded Expression of IRF4 Coordinates Isotype Switching with Plasma Cell Differentiation

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NIAID Data Ecosystem2026-03-07 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE6337
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资源简介:
Determine irf4 target genes in mouse B cells undergoing LPS differentiation to plasma cells in vitro. Determine targets of IRF4 by overexpression in a human GCB cell line. Keywords: cell type comparison design Mouse lymphochip arrays consisted of a reference pool vs mouse Irf4+/- and mouse Irf4-/- samples. Human lymphochip arrays consisted of non-transduced vs IRF-4-transduced human cell line Oci-Ly7. Design included biological repeats at each time point. Only data from sequence-verified features were published. The mouse lymphochip consists of 701 confirmed features.
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2013-01-17
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