Immunologic predictors for clinical responses during immune checkpoint blockade in patients with myelodysplastic syndromes. Immunologic predictors for clinical responses during immune checkpoint blockade in patients with myelodysplastic syndromes

We investigated the immune-related gene expression signature in the tumor immune-microenvironment associated with response or resistance during immunotherapy, by performing targeted gene expression profiling and gene set enrichment analysis using a custom NanoString panel composed of 579 immune-related genes Overall design: Peripheral blood from 55 MDS patients were assessed for immune-related gene expression profiling pre and after the first treatment