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Transcription profiling of mouse cardiac muscle from wild type and mdx mice, 8 week and 10.5 month (Porter lab)

ChEBI2008-06-11 更新2026-07-21 收录

心肌转录组学

肌营养不良模型

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-1471 数据链接链接失效反馈

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资源简介：

Transcription profiling of mouse cardiac muscle from wild type and mdx mice, 8 week and 10.5 month (Porter lab)

应用场景：

创建时间：

2008-06-11

肌营养不良模型

干细胞分化

Facioscapulohumeral muscular dystrophy (FSHD) represents a majorunmet clinical need arising from the progressive weakness and atrophy of skeletal muscles. The dearth of adequate experimental models ha

NIAID Data Ecosystem90

Targeted genome editing in vivo corrects a Dmd duplication restoring wild‐type dystrophin expression

基因编辑治疗

肌营养不良模型

Tandem duplication mutations are increasingly found to be the direct cause of many rare heritable diseases, accounting for up to 10% of cases. Unfortunately, animal models recapitulating such mutation

NIAID Data Ecosystem60

Dystrophin-deficient and dystrophin and utrophin double-deficient mice crossed with mice with full-length hDMD genes. Mus musculus

肌营养不良模型

基因治疗

Crossing of hDMD mice that contain the full-length 2.3 Mb hDMD gene were crossed with dystrophin-deficient mdx mice and dystrophin and utrophin double-deficient mdx x utrn-/- mice resulted in a full r

NIAID Data Ecosystem50

Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and NS-DADm mice myocardium Transcriptomes. Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and NS-DADm mice myocardium Transcriptomes

心肌转录组学

差异基因表达分析

Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this study are to compare NGS-derived heart transcriptome profiling (RNA-seq) to

NIAID Data Ecosystem90

Cardiac Resynchronization Therapy (2-color design). Canis lupus familiaris

心脏再同步治疗

心肌转录组学

Objectives: To test whether (1) electromechanical dyssynchrony induces region-specific alterations in the myocardial transcriptome and (2) dyssynchrony-induced gene expression changes can be corrected

NIAID Data Ecosystem50

Transcription profiling of mouse cardiac muscle from wild type and mdx mice, 8 week and 10.5 month (Porter lab)

资源简介：

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