Dataset 4 - Induction of HA stalk-reactive antibodies by H3 viruses

B cells from healthy donors were stimulated with CpG 2006 ODN alone or together with inactivated A/Vic11 viruses, A/SH13 (H7N9), and A/Hong Kong/33982/2009 (A/HK09) (H9N2) and pandemic H1N1 viruses. The levels of IgG against H3 HA, H5 head and chimeric molecules cH5/3 are shown for individual honors. (A) Nine of 13 donors displayed increases in stalk-reactive IgG after A/Vic11 stimulation. (B, C) A correlation model assuming different coefficients for different H3N2 strains-specific antibodies was fitted to evaluate the relationship between HA stalk-reactive and strain-specific IgG.