Crystal structure of Enterococcus Faecium D63r Penicillin-Binding protein 5 (PBP5fm)

Crystal structure of Enterococcus Faecium D63r Penicillin-Binding protein 5 (PBP5fm) Descriptor: (2R)-2-[(1R)-1-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino}-2-oxoethyl]-5-({2-oxo-1-[(3R)-pyr rolidin-3-yl]-2,5-dihydro-1H-pyrrol-3-yl}methyl)-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Low affinity penicillin-binding protein 5 (PBP5), SULFATE ION Authors: Sauvage, E, El Gachi, M, Herman, R, Kerff, F, Charlier, P. Deposit date: 2018-04-08 Release date: 2019-04-24 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structural basis of inactivation of Enterococcus faecium penicillin binding protein 5 by ceftobiprole. To Be Published