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Crystal structure of human KDM4A in complex with compound 58

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Protein Data Bank Japan2024-01-10 更新2026-03-21 收录
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Crystal structure of human KDM4A in complex with compound 58 Descriptor: 1,2-ETHANEDIOL, 3H-pyrido[3,4-d]pyrimidin-4-one, DIMETHYL SULFOXIDE, ... Authors: Le Bihan, Y.-V, Dempster, S, Westwood, I.M, van Montfort, R.L.M. Deposit date: 2015-12-02 Release date: 2016-01-20 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.22 Å) Cite: 8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors. J.Med.Chem., 59, 2016

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2015-12-02
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