Effect of Maternal Non-Nutritive Sweeteners diet on the progenies' gut microbiome. Mus musculus

Non-nutritive sweeteners (NNS) are marketed as sugar alternatives providing sweet taste with few or no calories. Yet their consumption has been linked to metabolic dysfunction and changes in the gut microbiome. NNS exposure mostly originates from diet beverages and sweetener packages in adults or breastmilk in infants. Consequences of early life exposure remain largely unknown. This project aims to understand the impact of pre- and post-natal exposure to NNS on microbiome and metabolism.