Original data for the manuscript of “Synergistic Bioactive and Antibacterial Surface Engineering of Polyetheretherketone (PEEK) via Silver/Calcium Phosphate(Ag/CaP) Composite Coatings”

This study developed a Silver-Calcium Phosphate (Ag/CaP) composite coating on Polyetheretherketone (PEEK) to enhance bioactivity and antibacterial performance. PEEK surfaces were first nanostructured via low-temperature argon plasma treatment, followed by polydopamine (PDA) polymerization as a bioadhesive platform. Silver nanoparticles were then deposited through redox reactions, and a calcium phosphate (CaP) layer was chemically applied. Surface characterization by SEM, EDS, XRD, and contact angle measurements confirmed nanoscale grooves, uniform nanoparticle distribution, and increased hydrophilicity. Biological assays using mouse embryonic osteoblasts (MC3T3) demonstrated significant improvements in cell adhesion, proliferation, and osteogenic differentiation, as indicated by enhanced alkaline phosphatase activity. Antibacterial testing against Staphylococcus aureus and Escherichia coli revealed over 90% inhibition rates for both Ag/PEEK and CaP/Ag/PEEK coatings. The results suggest that the synergistic effects of Ag and CaP coatings promote bone regeneration and infection resistance, highlighting the potential of this surface modification strategy for orthopedic implant applications.