官方服务:
资源简介:
MAGeCK analysis of tiling CRISPR screen data
应用场景:
创建时间:
2020-07-10
相关数据集
LKB1 drives stasis and C/EBP-mediated reprogramming to an alveolar type II fate in lung cancer [Primary Tuba-seq]
Background: LKB1 is among the most frequently altered tumor suppressors in lung adenocarcinoma. Inactivation of Lkb1 accelerates the growth and progression of oncogenic KRAS-driven lung tumors in mous
NIAID Data Ecosystem20
CRISPR screen for interferon-alpha inducible inhibitors of yellow fever virus replication
Host cells produce interferon (IFN) in response to viral infections. Secreted interferon results in the transcription and production of hundreds of interferon-stimulated genes (ISGs). A genome-wide CR
NIAID Data Ecosystem10
Convergent identification and interrogation of tumor-intrinsic factors for immune escape in vivo
Evading immune destruction is a hallmark of cancer and a key feature for theresistance to cancer immunotherapy. Genetic alterations can directly influence thenature of cancer cells in the native tumor
NIAID Data Ecosystem10
Genome_scale_identification_of_cellular_pathways_required_for_cell_surface_recognition. Genome_scale_identification_of_cellular_pathways_required_for_cell_surface_recognition
Interactions mediated by cell surface receptors initiate important instructive signaling cues but can be difficult to detect in biochemical assays because they are often highly transient and membrane-
NIAID Data Ecosystem20
Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors
The ongoing SARS-CoV-2 pandemic has devastated the global economy and claimed more than one million lives, presenting an urgent global health crisis. To identify host factors required for infection by
NIAID Data Ecosystem10



