Additional file 1 of Precision integrated identification of predictive first-trimester metabolomics signatures for early detection of gestational diabetes mellitus

Supplementary Material 1: Table S1: Complete List of Metabolites with Annotations (Post-Preprocessing and Merging). Table S2: Details of all metabolites associated with GDM. Table S3: Prediction Performance Metrics of All Metabolite Panels for GDM. Figure S1: Study design. Figure S2: Metabolomics data QC work flow. Figure S3: Non-Polar Negative Data - Standardized. Boxplot of all the non-polar negative metabolites on x-axis and adjusted for the batch effect and scaled metabolite frequencies on y-axis. Figure S4: Non-Polar Positive Data - Standardized. Boxplot of all the non-polar positive metabolites on x-axis and adjusted for the batch effect and scaled metabolite frequencies on y-axis. Figure S5: Polar Positive Data - Standardized. Boxplot of all the polar metabolites on x-axis and adjusted for the batch effect and scaled metabolite frequencies on y-axis. Figure S6: A violin plot representing metabolites distribution across normal and GDM. Figure S7: Permutation test distribution of AUC.