The FK1 domain of FKBP51 in complex with the macrocyclic SAFit analog 29c

The FK1 domain of FKBP51 in complex with the macrocyclic SAFit analog 29c Descriptor: (2~{S},9~{S},12~{S})-2-cyclohexyl-20,23-dimethoxy-12-methyl-11,14,18-trioxa-4-azatricyclo[17.2.2.0^{4,9}]tricosa-1(22),19(23),20-triene-3,10-dione, Peptidyl-prolyl cis-trans isomerase FKBP5 Authors: Meyners, C, Brudy, C, Hausch, F. Deposit date: 2025-03-06 Release date: 2025-12-03 Last modified: 2025-12-24 Method: X-RAY DIFFRACTION (1.74 Å) Cite: Linker Modification Enables Control of Key Functional Group Orientation in Macrocycles. J.Med.Chem., 68, 2025