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Transient gene melting governs the timing of oligodendrocyte maturation. Transient gene melting governs the timing of oligodendrocyte maturation

NIAID Data Ecosystem2026-03-13 收录

胶质细胞发育

表观遗传调控

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA809729 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2022-02-23

2型糖尿病族群遗传学

表观遗传调控

BackgroundDue to the distinctive living environment, lifestyle, and diet, the Tibetan community in China has the lowest prevalence of T2DM and prediabetes among numerous ethnic groups, while Han commu

NIAID Data Ecosystem10

Reduction of DNA Topoisomerase Top2 reprograms the epigenetic landscape and extends health and life span across species

抗衰老干预

表观遗传调控

DNA topoisomerases are essential molecular machines that manage DNA topology in the cell and play important roles in DNA replication and transcription. We find that knocking down the enzyme Topoisomer

NIAID Data Ecosystem00

Histone H3K27ac extension and intergenic transcription from enhancers activate close erythroid genes in a TAL1-independent manner [ChIP-seq]

表观遗传调控

ChIP-seq分析

Erythroid genes having enhancers in a short distance appear to be transcriptionally activated by histone H3K27ac extension and intergenic transcription that are independent from TAL1. Overall design:

NIAID Data Ecosystem00

Developmental origin of oligodendrocytes determines their function in the adult brain

胶质细胞发育

神经髓鞘功能

The functional importance of oligodendrocyte developmental heterogeneity is unknown. Using a genetic strategy to ablate dorsally-derived oligodendrocyte lineage cells (OLCs), we found that the areas i

NIAID Data Ecosystem00

DNA methylation status determines the sensitivity of repeats to restriction by the HUSH-MORC2 complex [ONT cDNA sequencing]

表观遗传调控

重复序列沉默机制

The human silencing hub (HUSH) complex binds to transcripts of LINE-1 retrotransposons (L1s) and other genomic repeats, recruiting MORC2 and other effectors to remodel chromatin. However, how HUSH and

NIAID Data Ecosystem00

Transient gene melting governs the timing of oligodendrocyte maturation. Transient gene melting governs the timing of oligodendrocyte maturation

资源简介：

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