MicroRNA-SEQ analysis of kidney and liver damage in rat. Rattus norvegicus

Purpose : Identification of novel microRNA biomarkers in urine and plasma from rats with kidney or liver damage Overall design: micoRNA-SEQ was used to analyze changes in miRNA profiles of tissue, plasma and urine samples of rats treated with either a nephrotoxicant (cisplatin) or one of two hepatotoxicants (Acetaminophen [APAP] or Carbon Tetrachloride [CCL4]).