Truth table of the expression patterns of the Or59b cluster experiments.

In the four left columns the mutation table for the cluster motifs Acj6Hox, Pdm3Hox, Pou and Ebox is shown: 0 corresponds to mutated motif and 1 to unaltered motif. The 3 rightmost columns represent the expression driven by the Or59b cluster in Or59b receptors, in our model identified with . Values are between 0 (total loss) and 1 (very strong expression), see also Fig 1(B) and Table A of S1 Text. The 3 columns correspond to chromatin in its normal state (“closed”, column C), heterozygous mutation of su(var)3-9 (“open”, column H) and homozygous mutation of su(var)3-9 (“more open”, column N). Yellow cells represent configurations which have beed directly experimented in [26], green cells are configurations tested in an indirect way in [26], orange and blue cells are novel direct and indirect experiments. Gray cells correspond to experiments with mutated Ebox, which can all be marked as total loss. When a direct/indirect experiment is missing the cell is left white. The ranges [ℓ, u] = [upper bound, lower bound] are given according to our quantification of the GFP reporter fused to the TATA box. More details of this quantification are given in Table A of S1 Text. For E8, E12, E14 and E16, GFP expression on selected flies is shown in Fig 5(A)–5(C), and in Fig 1(C). For missing experiments a maximal range is chosen, i.e., [ℓ, u] = [0, 1] (except for E2 which always leads to loss of expression).