<b>CpG Analysis of Intergenic Regions in BM48-31/BGR/2008 (Bat Coronavirus)</b>

This project analyzes the distribution of CpG sites in the intergenic regions of the BM48-31/BGR/2008 bat coronavirus genome. The analysis provides insights into the genomic characteristics of this virus, highlighting regions with potential functional significance.<br>Key findings include:- Significant variation in CpG counts across intergenic regions, with one region (`Intergenic_Region_1`) showing a markedly higher count (183 CpG sites).- Observed/expected (O/E) ratios reveal both enrichment and depletion patterns, reflecting evolutionary pressures such as host immune evasion and mutational biases.- Most intergenic regions exhibit low or negligible CpG content, consistent with CpG depletion commonly observed in coronaviruses.<br>The dataset includes:- A tab-delimited file (`BM48-31_cpg_analysis.txt`) containing CpG counts and O/E ratios for each intergenic region.- Visualizations: - Bar chart showing CpG counts across regions. - Line plot illustrating O/E ratios.- Python scripts used for extracting intergenic regions, calculating CpG metrics, and generating plots.<br>This work contributes to understanding the genomic architecture of BM48-31/BGR/2008 and its evolutionary strategies. The analysis was performed using Biopython, Pandas, and Matplotlib.