File S1 - Biochemical Characterization of Human Gluconokinase and the Proposed Metabolic Impact of Gluconic Acid as Determined by Constraint Based Metabolic Network Analysis

The file contains five worksheets that report the following 1: measured luminesence values from the substrate specificity assays 2: results from flux variability analysis of in iAB-RBC-283 with and without gluconate. 3: how flux values relate to arrow thickness as portrayed in figure 4. 4: Calculated shadow prices in the presence and absence of gluconate. 5: FBA solutions obtained upon relaxing transport/exchange flux boundaries in the presence and absence of gluconate. (XLSX)