Crystal Structure of T190I SARS-CoV-2 Main Protease in Complex with Compound Mpro61

Crystal Structure of T190I SARS-CoV-2 Main Protease in Complex with Compound Mpro61 Descriptor: (5P)-5-[(1P,3M,3'P)-3-{3-chloro-5-[(2-chlorophenyl)methoxy]-4-fluorophenyl}-2-oxo-2H-[1,3'-bipyridin]-5-yl]-1-methylpyrimidine-2,4(1H,3H)-dione, 3C-like proteinase nsp5 Authors: Papini, C, Zhang, C.H, Jorgensen, W.L, Anderson, K.S. Deposit date: 2024-05-03 Release date: 2025-02-12 Last modified: 2025-03-12 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Exploring Possible Drug-Resistant Variants of SARS-CoV-2 Main Protease (M pro ) with Noncovalent Preclinical Candidate, Mpro61. Acs Bio Med Chem Au, 5, 2025