Demographic and clinical characteristics of schizophrenia subjects and unaffected siblings.

Abbreviations: CI, confidence interval; SANS, Schedule for the Assessment of Negative Symptoms; SAPS, Schedule for the Assessment of Positive Symptoms; SD, standard deviation; WRAT-3, Wide Range Achievement Test, 3rd edition.aUnaffected siblings represent 279 families, of which 17 (6%) were multiplex.bBetween-group P values are based on generalized linear mixed-effects models for categorical variables and linear mixed-effects models for continuous variables; P values were not computed for race, multiplex status, parental education, or age at onset of symptoms.cFor continuous variables, differences between groups (probands – unaffected siblings) and 95% CIs for differences are based on linear mixed-effects models; for categorical variables, odds ratios and 95% CIs for odds ratios are based on generalized linear mixed-effects models. CIs are shown only for variables where the P value for the between-group test is d4 missing values for schizophrenia subjects; 2 missing values for unaffected siblings.eMultiplex families were those for which at least one parent or sibling of the proband had a history of schizophrenia or schizoaffective disorder.f2 missing values for schizophrenia subjects; 2 missing values for unaffected siblings.g6 missing values for schizophrenia subjects; 3 missing values for unaffected siblings.h10 missing values for schizophrenia subjects; 12 missing values for unaffected siblings.i5 missing values for schizophrenia subjects.j7 missing values for schizophrenia subjects; 73 missing values for unaffected siblings.k7 missing values for schizophrenia subjects; 74 missing values for unaffected siblings.