Adora1

Predicted to enable several functions, including G protein-coupled adenosine receptor activity; G-protein beta/gamma-subunit complex binding activity; and heterotrimeric G-protein binding activity. Involved in regulation of sensory perception of pain. Acts upstream of or within several processes, including excitatory postsynaptic potential; negative regulation of long-term synaptic depression; and negative regulation of mucus secretion. Located in dendritic spine. Is expressed in several structures, including adipose tissue; alimentary system; brain; genitourinary system; and heart. Human ortholog(s) of this gene implicated in asthma. Orthologous to human ADORA1 (adenosine A1 receptor). [provided by Alliance of Genome Resources, Nov 2024]

该数据集预测将启用多种功能，包括G蛋白偶联腺苷受体活性；G蛋白β/γ亚基复合物结合活性；以及异源三聚体G蛋白结合活性。涉及痛觉感知的调节。在多个过程中发挥上游或内部作用，包括兴奋性突触后电位；长期突触抑制的负调节；以及粘液分泌的负调节。位于树突棘。在多种结构中表达，包括脂肪组织；消化系统；大脑；泌尿生殖系统和心脏。该基因的人类同源基因与哮喘有关。与人类ADORA1（腺苷A1受体）同源。[由基因组资源联盟提供，2024年11月]