Subject clinical characteristics.

Clinical characteristics of the 25 Systemic Sclerosis subjects from which skin biopsies were taken are shown. Indicated for each subject are the age, sex, disease duration since first onset of non-Raynaud's symptoms, modified Rodnan skin score on a 51-point scale, a self-reported Raynaud's severity score on a 10-point scale, and the presence or absence of digital ulcers on a 3-point scale. Also indicated are the presence (+) or absence (?) of gastrointestinal involvement (GI), interstitial lung disease (ILD) as determined by high-resolution computerized tomography (HRCT), and renal disease. The age and sex of subjects with Morphea are: Morph1 (49 yrs, female, disease duration 16 yrs), Morph2 (54 yrs, female, disease duration 7 yrs), and Morph3 (49 yrs, female, disease duration 4 yrs). The age and sex of healthy control subjects are as follows: Nor1, 53 yrs, female; Nor2, 47 yrs, female; Nor3, 41, female; Nor4, 26, female; Nor5, 45, male; Nor6, 29, female. ND = Not determined