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H3K36me3 protects the mouse epigenome from single nucleotide variations [CGH]

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NIAID Data Ecosystem2026-03-12 收录
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Copy numbers of mouse cells (ESCs and NIH3T3) carrying a series of single-site histone mutants or shRNAs comparing with control empty cells. Genomic DNA from candidate cells and control cells were respectively labeled by Cy5 or Cy3 and analyzed by array-based comparative genomic hybridization (aCGH). multipule stable cell lines carrying histone mutants and shRNA against Suv39h1 or h2 were analyzed.

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2021-07-25
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