Design and synthesis of thiophene dihydroisoquinolins as novel BACE-1 inhibitors
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Design and synthesis of thiophene dihydroisoquinolins as novel BACE-1 inhibitors Descriptor: 2-{(1S)-1-{[(1Z)-6-chloro-3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene]amino}-2-[2-propyl-4-(1H-pyrazol-4-yl)thiophen-3-yl]ethyl}pyrimidin-4(5H)-one, Beta-secretase 1, SODIUM ION, ... Authors: Lougheed, J.C, Brecht, E, Yao, N.H. Deposit date: 2012-11-19 Release date: 2013-03-06 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Design and synthesis of thiophene dihydroisoquinolines as novel BACE1 inhibitors. Bioorg.Med.Chem.Lett., 23, 2013
创建时间：
2012-11-19
