five

Chromatin architecture in pediatric lupus

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https://www.ncbi.nlm.nih.gov/sra/SRP399492
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资源简介:
This project found changes in the DNA of children with lupus, more specifically, in portions of the DNA that are open and can be more easily-accessed for gene expression. In particular, stretches of DNA that appear to be important in readying genes important in the pro-inflammatory response for expression are more open in children with lupus than children without lupus. This may lead to new insights into the pathogenesis of lupus and targets for therapy.
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2023-01-02
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