ZRSR2 Mutant Myelodysplastic Syndromes

NIAID Data Ecosystem2026-04-25 收录

骨髓增生异常综合征

血液肿瘤基因突变分析

数据链接：

https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs002212.v1.p1 数据链接链接失效反馈

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Samples were included if the diagnosis was confirmed to be myelodysplastic syndromes. Samples were excluded if they had mutations in any of the following splicing factor genes: SF3B1, SRSF2 or U2AF1. Both male and females patients were included. ]]>

创建时间：

2020-08-14

Supplementary Material for: Copper Deficiency Mimicking Myelodysplastic Syndrome: Zinc Supplementation in the Setting of COVID-19

铜缺乏症

骨髓增生异常综合征

While copper deficiency is rare, it can have serious consequences, including pancytopenia and neuropathy. This treatable vitamin deficiency can present very similarly to myelodysplastic syndrome (MDS)

DataCite Commons2023-07-22 更新80

Synthetic lethal interactions and convergent biological effects underlie the mutual exclusivity of MDS-associated spliceosomal gene mutations

剪接体功能研究

骨髓增生异常综合征

RNA splicing factor mutations constitute the most common class of alterations in myelodysplastic syndromes (MDS). These occur as heterozygous mutations at restricted residues in SF3B1, SRSF2, and U2AF

NIAID Data Ecosystem40

Depletion of tet2 results in age-dependent changes in DNA methylation and gene expression in a zebrafish model of myelodysplastic syndrome [DNAmethylation]

骨髓增生异常综合征

DNA甲基化动态

Myelodysplastic Syndrome (MDS) is a heterogenous group of clonal hematopoietic disorders characterized by ineffective hematopoiesis, cytopenias and dysplasia. The gene encoding Ten-ele¬ven translocati

NIAID Data Ecosystem30

ABIN1 (Q478) is required to prevent hematopoietic deficiencies through regulating type I IFNs expression. ABIN1 (Q478) is required to prevent hematopoietic deficiencies through regulating type I IFNs expression

骨髓增生异常综合征

干细胞转录组学

A20-binding inhibitor of NF-κB activation (ABIN1) is a polyubiquitin-binding protein that regulates cell death and immune responses. Although Abin1 (Tnip1) is located on chromosome 5q in the region co

NIAID Data Ecosystem40

The Bone marrow stroma in human myelodysplastic syndrome reveals alterations that regulate disease progression [CD34+CD38-_MDS]

骨髓增生异常综合征

骨髓微环境免疫调节

Myelodysplastic syndromes (MDS) are a heterogenous group of diseases affecting the hematopoietic stem cell that are curable only by stem cell transplantation. Both hematopoietic cell intrinsic changes

NIAID Data Ecosystem30

ZRSR2 Mutant Myelodysplastic Syndromes

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