One-Pot Sonogashira Coupling–Cyclization toward Regioselective Synthesis of Benzosultams
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A one-pot method for the Sonogashira coupling and cyclization of 2-bromobenzenesulfonamides and terminal alkynes is presented. This method allows access to a variety of substituted benzosultams regioselectively in excellent yields. The reasons for regioselectivity are interpreted through density functional theory (DFT) studies.
创建时间：
2016-02-13
