Crystal Structure of PI5P4KIIAlpha complex with BI-2536
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Crystal Structure of PI5P4KIIAlpha complex with BI-2536 Descriptor: 4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide, Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, SULFATE ION Authors: Chen, S, Ha, Y. Deposit date: 2021-06-10 Release date: 2021-06-30 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Pharmacological inhibition of PI5P4K alpha / beta disrupts cell energy metabolism and selectively kills p53-null tumor cells. Proc.Natl.Acad.Sci.USA, 118, 2021
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2021-06-10
