Additional file 2 of Assessment of hypoxia and oxidative-related changes in a lung-derived brain metastasis model by [64Cu][Cu(ATSM)] PET and proteomic studies

Additional file 2.Figure S1: Comparison of tumor volume (in mm3) in both brain structures (cortex and striatum), at D22, D23 and D24 after intracerebral tumor cell implantation (a). Mean ± SD, n = 12 rats for cortical BM at D22, n = 13 rats for cortical BM at D23, n = 10 rats for cortical BM at D24 and n= 8 rats for striatal BM whatever the time studies. *p < 0.05, two-way ANOVA followed by Tukey’s test. (b) Quantification of [64Cu][Cu(ATSM)] uptake, 24-h post-injection, into cortical BM and striatal BM. Mean ± SD, n=10 for cortical BM and n=8 for striatal BM. One sample t-test vs theorical value of 1 and Mann-Whitney for comparison rSUV between cortical BM and striatal BM.