EWS-FLI1 and HOXD13 control tumor cell plasticity in Ewing sarcoma
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2022-07-01
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LIN28B underlies the pathogenesis of a subclass of Ewing sarcoma. LIN28B underlies the pathogenesis of a subclass of Ewing sarcoma
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EWS::FLI cooperatively binds at GGAA microsatellites via DBD-a4 helix in TTC-466 [H3K27ac_CnT]
Multi-omics study of DBD-a4 helix of EWS::FLI to understand the underlying mechanism of transcriptional regulation in Ewing sarcoma cell line: TTC-466 In TTC-466 cells, we knock-down endogenous EWSR1:
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Insulin-like growth factor 2 mRNA-binding protein 3 modulates aggressiveness of Ewing sarcoma by regulating the CD164-CXCR4 axis. Insulin-like growth factor 2 mRNA-binding protein 3 modulates aggressiveness of Ewing sarcoma by regulating the CD164-CXCR4 axis
Ewing sarcoma (EWS) is the second most common bone and soft tissue-associated malignancy in children and young adults. It is driven by the fusion oncogene EWS/FLI1 and characterized by rapid growth an
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Identification of a novel FUS/ETV4 fusion and comparative analysis with other Ewing sarcoma fusion proteins [RNA-seq]
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Supplementary Table S6 from KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma
Excel file showing DEG and downregulated direct targets upon KDM6A or KDM6B knockout.
Figshare2025-11-14 更新40
