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Joint profiling of chromatin accessibility and gene expression in thousands of single cells

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NIAID Data Ecosystem2026-05-02 收录
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Here we describe sci-CAR, a combinatorial indexing strategy to jointly profile chromatin accessibility and mRNA in each of thousands of single cells. As a proof-of-concept, we apply sci-CAR to 4,825 cells comprising a time-series of dexamethasone treatment, as well as to 11,233 cells from the mouse kidney.
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2025-02-14
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