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Soleus Muscle of Aged PAPP-A-Deficient Mice. Mus musculus

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA329049
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资源简介:
Mice deficient in pregnancy-associated plasma protein-A (PAPP-A) have extended lifespan associated with decreased incidence and severity of degenerative diseases of age, such as cardiomyopathy and nephropathy. In this study, the effect of PAPP-A deficiency on aging skeletal muscle was investigated. Overall design: Whole-genome expression profiling was performed on soleus muscles from 18-month-old wild-type and PAPP-A knock-out mice of the same sex and from the same litter ('womb-mates').
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2016-07-14
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