Tlr13 is missing in primates but occurs in mice and rarely in other mammals while it can be found in non-mammalian vertebrates, insects, Annelida and plants.

Tlr13 orthologs were searched for and identified using the OMA browser (light blue) or a standard NCBI Blast search against non-redundant protein sequences (dark blue). Putative hits were tested for occurrence of similar feature architecture as in the query protein, i.e. mouse Tlr13, using FACT (Feature Architecture Comparison Tool; http://www.cibiv.at/FACT). Hits exhibiting similar protein architecture as mouse Tlr13 were defined as predicted orthologs and are depicted in light blue (hits obtained using the OMA browser) or dark blue (hits obtained using NCBI Blast). Shown is a choice of mammalian species as well as Tlr13-containing representatives from other kingdomes. (PDF)