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Crystal structure of FGFR2 in complex with 1,3,5-triazine derivative

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Protein Data Bank Japan2023-11-29 更新2026-03-21 收录
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Crystal structure of FGFR2 in complex with 1,3,5-triazine derivative Descriptor: Fibroblast growth factor receptor 2, N-ethyl-2-[[4-[[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amino]-1,3,5-triazin-2-yl]amino]benzenesulfonamide, SULFATE ION Authors: Echizen, Y, Tateishi, Y, Amano, Y. Deposit date: 2020-02-04 Release date: 2020-04-08 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.98 Å) Cite: Structure-based drug design of 1,3,5-triazine and pyrimidine derivatives as novel FGFR3 inhibitors with high selectivity over VEGFR2. Bioorg.Med.Chem., 28, 2020

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2020-02-04
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