PHYTOCHEMICAL PROFILING AND GCMS STUDY OF ADHATODA VASICA LEAVES

Adhatoda vasica (AV), a popular Indian medicinal plant, is a rich source of polyphenoliccompounds especially flavonoids which are responsible for strong anti-oxidantproperties that helps in the therapy of various respiratory diseases. In the presentinvestigation, phytochemical screening and gas chromatography mass spectrometryanalysis of AV leaves was carried out to evaluate the chemical composition in differentsolvent extraction which could be useful in future experimental studies. Phytochemicalanalysis confirmed the presence of alkaloids, flavaones, flavanoids, phytosterols, fixedoils, saponins, phenolic compounds, tannins, carbohydrates and glycosides in theethanolic extract comparing to the other extracts. Interestingly, ten anti-inflammatorycompounds like terpene alcohol, diterpene, linolenic acid, alkaloid, vitamin, steroid andsesquiterpene oxide were identified through GC- MS analysis in both the ethanol andmethanol extract. In conclusion, the ethanol extract is more effective for extracting majoractive compounds and for therapeutic applications.