Structure-based design of potent and selective inhibitors of phospholipase A2: Crystal structure of the complex formed between phosholipase A2 from Naja Naja sagittifera and a designed peptide inhibitor at 1.9 A resolution

Protein Data Bank Japan2024-11-13 更新2026-03-21 收录

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Structure-based design of potent and selective inhibitors of phospholipase A2: Crystal structure of the complex formed between phosholipase A2 from Naja Naja sagittifera and a designed peptide inhibitor at 1.9 A resolution Descriptor: CALCIUM ION, Phospholipase A2, VAL-ALA-PHE-ARG-SER Authors: Singh, R.K, Vikram, P, Paramsivam, M, Jabeen, T, Sharma, S, Makker, J, Dey, S, Kaur, P, Srinivasan, A, Singh, T.P. Deposit date: 2002-08-09 Release date: 2003-09-30 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Design of specific peptide inhibitors for group I phospholipase A2: structure of a complex formed between phospholipase A2 from Naja naja sagittifera (group I) and a designed peptide inhibitor Val-Ala-Phe-Arg-Ser (VAFRS) at 1.9 A resolution reveals unique features Biochemistry, 42, 2003

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2002-08-09