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Systemic and topical OVA sensitization results in inflammation, disturbs epidermal barrier homeostasis, and induces PPARδ target gene expression in skin.

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https://figshare.com/articles/dataset/_Systemic_and_topical_OVA_sensitization_results_in_inflammation_disturbs_epidermal_barrier_homeostasis_and_induces_PPAR_948_target_gene_expression_in_skin_/774115
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e.c., epicutaneous; i.p., intraperitoneal; OVA, ovalbumin; Th, T-helper cell. 1Enumerated twice because the gene is relevant for two pathways. Fold change data are expressed as mean ± SEM (n = 6) and were determined in skin specimen of sensitized mice by TLDA or qRT-PCR. Statistical significance (p) was tested using one-way ANOVA followed by Tukey’s multiple comparison test. *p<0.05, **p<0.01, ***p<0.001, versus control (PBS i.p.); #p<0.05, ##p<0.01, and ###p<0.001, versus OVA i.p.
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2013-08-15
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