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SLFN11-mediated ribosome biogenesis impairment induces TP53-independent apoptosis

NIAID Data Ecosystem2026-05-02 收录

核糖体生物合成

细胞凋亡机制

数据链接：

https://data.mendeley.com/datasets/m8cn79mrcs 数据链接链接失效反馈

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Unprocessed pictures, gel images, and plasmid information used in the corresponding paper.

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创建时间：

2025-01-27

细胞凋亡机制

p53信号通路

17β-Estradiol (E2) is the major estrogen secreted by the premenopausal ovary and shows dual effects on cell apoptosis under pathological conditions. E2 was previously shown to increase CD38 mRNA and p

NIAID Data Ecosystem260

Runx1 deficiency decreases ribosome biogenesis and confers stress resistance to hematopoietic stem and progenitor cells

造血干祖细胞

核糖体生物合成

The transcription factor RUNX1 is frequently mutated in myelodysplastic syndrome and leukemia. RUNX1 mutations can be early events, creating pre-leukemic stem cells that expand in the bone marrow. Her

NIAID Data Ecosystem70

Gene expression in EBV-positive versus EBV-loss clones derived from endemic Burkitt lymphoma cell lines

EBV基因表达

细胞凋亡机制

Whilst the association of Epstein-Barr virus (EBV) with Burkitt lymphoma (BL) has long been recognized, the precise role of the virus in BL pathogenesis is not fully resolved. EBV can be lost spontane

NIAID Data Ecosystem60

Developmental expression patterns of zebrafish caspases.

发育生物学

细胞凋亡机制

Developmental expression patterns of zebrafish caspases.

NIAID Data Ecosystem70

TNF-alpha Signalling Pathway

TNF信号通路

细胞凋亡机制

The Tumor Necrosis Factor alpha is a proinflammatory cytokine belonging to the TNF superfamily. It signals through 2 separate receptors - TNFRSF1A and TNFRSF1B, both members of the TNF receptor superf

NIAID Data Ecosystem70

SLFN11-mediated ribosome biogenesis impairment induces TP53-independent apoptosis

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