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METTL1 coordinates tumor progression of cutaneous squamous cell carcinoma via m7G modification

NIAID Data Ecosystem2026-05-01 收录

RNAm7G修饰

皮肤癌机制

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1102036 数据链接链接失效反馈

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To systematically explore the mechanism of METTL1 in promoting cSCC tumorigenesis, we conducted bulk RNA-seq analysis to identify differentially expressed genes (DEG) in METTL1-knockdown and control cells.

应用场景：

创建时间：

2024-04-18

毛囊分化调控

皮肤癌机制

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Epidermal fatty acid binding protein prevents chemical-induced skin tumorigenesis by inhibition of SOX2 expression in keratinocytes. Epidermal fatty acid binding protein prevents chemical-induced skin tumorigenesis by inhibition of SOX2 expression in keratinocytes

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肿瘤抑制基因

E-FABP expression in keratinocytes increase interferons, in particualur IFNlamda, expression, which activate P53, a critical tumor suppessor, to inhibit or prevent chemical-induced skin tumorigenesis.

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microRNAs Restrain Proliferation in BRAFV600E Melanocytic Nevi [RNA-Seq]. microRNAs Restrain Proliferation in BRAFV600E Melanocytic Nevi [RNA-Seq]

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RNA测序分析

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Murine Kdm6a and Trp53 null squamous cell carcinoma

皮肤癌机制

表观遗传调控

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Galectin-7 reprograms skin carcinogenesis by fostering innate immune evasive programs

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METTL1 coordinates tumor progression of cutaneous squamous cell carcinoma via m7G modification

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