Kinetic modeling of enzymatic cephalexin synthesis with neural ODEs and surro...

α-Amino ester hydrolases (AEHs) offer a promising route to the stereoselective synthesis of β-lactams such as cephalexin. However, published kinetic studies have encountered...α-氨基酸酯水解酶（α-Amino ester hydrolases，AEHs）为头孢氨苄（cephalexin）等β-内酰胺类（β-lactams）化合物的立体选择性合成提供了极具潜力的途径。然而，已发表的动力学研究仍面临……