N‑Heterocyclic Carbene–Palladium(II)–4,5-Dihydrooxazole Complexes: Synthesis and Catalytic Activity toward Amination of Aryl Chlorides

A series of novel N-heterocyclic
carbene–palladium­(II)–4,5-dihydrooxazole
(NHC-PdII-Ox) complexes 3 were successfully
synthesized from commercially available imidazolium salts 1, PdCl2, and 4,5-dihydrooxazoles 2 in a one-step
process, and these complexes showed efficient catalytic activity toward
the amination of aryl chlorides. Both secondary and primary amines
were tolerated under the same reaction conditions. Under the optimal
reaction conditions, the expected coupling products were obtained
in moderate to high yields.