Ternary complex between VCB, BRD4-BD2 and PROTAC 48
收藏Protein Data Bank Japan2024-02-07 更新2026-04-19 收录
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Ternary complex between VCB, BRD4-BD2 and PROTAC 48 Descriptor: (2S,4R)-N-[(1S)-1-(4-chlorophenyl)-3-[2-[2-[2-[2-[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8$l^{5},11,12-tetrazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]ethanoylamino]ethoxy]ethoxy]ethoxy]ethylamino]-3-oxidanylidene-propyl]-1-[(2R)-3-methyl-2-(3-methyl-1,2-oxazol-5-yl)butanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Bromodomain-containing protein 4, Elongin-B, ... Authors: Sorrell, F.J, Mueller, J.E, Lehmann, M, Wegener, A. Deposit date: 2022-10-20 Release date: 2023-02-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.93 Å) Cite: Systematic Potency and Property Assessment of VHL Ligands and Implications on PROTAC Design. Chemmedchem, 18, 2023
创建时间：
2022-10-20
