five

Crystal structure of the human CDK2 complexed with the triazolopyrimidine inhibitor

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Protein Data Bank Japan2023-12-13 更新2026-03-21 收录
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Crystal structure of the human CDK2 complexed with the triazolopyrimidine inhibitor Descriptor: (5Z)-5-(3-BROMOCYCLOHEXA-2,5-DIEN-1-YLIDENE)-N-(PYRIDIN-4-YLMETHYL)-1,5-DIHYDRO[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-AMINE, CELL DIVISION PROTEIN KINASE 2 Authors: Richardson, C.M, Dokurno, P, Murray, J.B, Surgenor, A.E. Deposit date: 2005-11-08 Release date: 2005-12-07 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Triazolo[1,5-a]pyrimidines as novel CDK2 inhibitors: protein structure-guided design and SAR. Bioorg. Med. Chem. Lett., 16, 2006
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2005-11-08
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