Disrupted CEP128 function impairs spermatogenesis
收藏NIAID Data Ecosystem2026-03-13 收录
下载链接：
https://www.ncbi.nlm.nih.gov/sra/SRP356255
下载链接
链接失效反馈官方服务：
资源简介：
The centrosome is a conserved eukaryotic organelle essential to the reproductive process, and centrosomal proteins are necessary components of the centrosome. However, few centrosomal proteins have been genetically linked to fertility, and the related molecular mechanisms remain unknown. Herein we identified a homozygous missense variant of CEP128 in two infertile males with cryptozoospermia from a consanguineous family.Altogether, our findings unveil in unprecedented fashion a crucial role for CEP128 in male fertility and provide new insights into the functions of centrosomal proteins in reproductive biology.
创建时间：
2022-01-23
