Estrogen receptor beta excerts tumorsuppressive effects in prostate cancer through repression of androgen receptor activity
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We found that ERbeta activated by ligand eithe E2 or LY3201 repressed AR activity and affected downstream genes regulated by AR Overall design: To investigate the mechanisms of action of ERÃ and its potential cross-talk with AR, we used RNA-seq to study the effects of estradiol or the synthetic ligand, LY3201, in AR-positive LNCaP PCa cells which had been engineered to express ERÃ.
创建时间：
2020-06-09
