Crystal structure of Bace1 with its inhibitor
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Crystal structure of Bace1 with its inhibitor Descriptor: Beta-secretase 1, METHYL (2R)-1-[(6S,9S,12S,13S,17S,20S,23R)-9-(3-AMINO-3-OXOPROPYL)-12,23-DIBENZYL-13-HYDROXY-2,2,8,20,22-PENTAMETHYL-17-(2-METHYLPROPYL)-4,7,10,15,18,21,24-HEPTAOXO-6-(PROPAN-2-YL)-3-OXA-5,8,11,16,19,22-HEXAAZATETRACOSAN-24-YL]PYRROLIDINE-2-CARBOXYLATE, SULFATE ION Authors: Chen, T.T, Chen, W.Y, Li, L, Xu, Y.C. Deposit date: 2011-11-21 Release date: 2012-11-21 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Cyanobacterial Peptides as a Prototype for the Design of Potent beta-Secretase Inhibitors and the Development of Selective Chemical Probes for Other Aspartic Proteases J.Med.Chem., 55, 2012
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2011-11-21
