Gene expression profile during senescence induced by LSG1 knockdown
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE128055
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资源简介：
In the present study, we analyze the effect of knocking down LSG1 and KRas(V12D) overexpression in MRC5 cells in the transcriptome using Ampliseq RNA sequencig. We observed that shLSG1 induced a potent senescence response that is characterized by the activation of ER-Stress and cholesterol biosynthetic pathway MRC5 were transfected with siRNA to knockdown the small GTPase LSG1. Total mRNA was extracted and expression profiles were analyzed.
创建时间：
2019-07-03
