Chemical compounds targeting NTCP-mediated HBV entry.
收藏NIAID Data Ecosystem2026-03-13 收录
数据链接：
官方服务：
资源简介：
Chemical compounds targeting NTCP-mediated HBV entry.
应用场景：
创建时间：
2022-03-21
相关数据集
Table_2_Establishment of a human cell line with a surface display system for screening and optimizing Na+-taurocholate cotransporting polypeptide-binding peptides.XLSX
One of the most desirable targets for HBV medications is the sodium taurocholate cotransporting polypeptide (NTCP), an entry receptor for the hepatitis B virus (HBV). N-myristoylated preS1 2–48 (Myrcl
frontiersin.figshare.com2023-06-16 更新130
Effect of two compounds on HBV gene expression in HBV-infected primary human hepatocytes.
HBV gene expression in HBV-infected primary human hepatocytes. Comparative time-series gene expression profiling analysis of HBV RNA-seq data derived from cultured primary human hepatocytes treated wi
NIAID Data Ecosystem30
Discovery of Novel Pyrimidine-Based Capsid Assembly Modulators as Potent Anti-HBV Agents
Core assembly modulators of viral capsid proteins have been developed as an effective treatment of chronic hepatitis B virus (HBV) infection. In this study, we synthesized novel potent pyrimidine deri
Figshare2021-04-23 更新30
Discovery of a Hepatitis C Virus NS5B Replicase Palm Site Allosteric Inhibitor (BMS-929075) Advanced to Phase 1 Clinical Studies
The hepatitis C virus (HCV) NS5B replicase is a prime target for the development of direct-acting antiviral drugs for the treatment of chronic HCV infection. Inspired by the overlay of bound structure
NIAID Data Ecosystem80
Characterization of a KDM5 Small Molecule Inhibitor with Antiviral Activity in Rodent Livers
Chronic hepatitis B (CHB) is a global health care challenge and a major cause of liver disease. Existing therapies do not result in a functional cure in most individuals, necessitating new antiviral s
NIAID Data Ecosystem30
