Discovery of TAK-272: A Novel, Potent and Orally Active Renin In-hibitor
收藏Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
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Discovery of TAK-272: A Novel, Potent and Orally Active Renin In-hibitor Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-~{tert}-butyl-4-(furan-2-ylmethylamino)-~{N}-(2-methylpropyl)-~{N}-[(3~{S})-piperidin-3-yl]pyrimidine-5-carboxamide, DI(HYDROXYETHYL)ETHER, ... Authors: Snell, G.P, Behnke, C.A, Okada, K, Hideyuki, O, Sang, B.-C, Lane, W. Deposit date: 2016-07-01 Release date: 2016-11-02 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structure-based design of a new series of N-(piperidin-3-yl)pyrimidine-5-carboxamides as renin inhibitors. Bioorg.Med.Chem., 24, 2016
创建时间：
2016-07-01
