Summary of HIV resistance mutations obtained from ultra-deep sequencing (UDS) study.
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https://figshare.com/articles/dataset/_Summary_of_HIV_resistance_mutations_obtained_from_ultra_deep_sequencing_UDS_study_/945101
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aAnalyzed for HIV from VTC subjects only.
1ART: K103N, E138A, Y181C, H221Y; PR: M46I, Q58E.
1BRT: M41L, D67N, K70R, V75I, V90I, A98G, K101E, K101P, K103N, K103S, V106I, V106M, V108I, E138A, E138G, E138K, Q151M, V179D, Y181C, M184I, M184V, Y188L, G190A, L210W, T215Y, K219E, K219Q, H221Y, P225H, M230I; PR: V32I, M46I, M46L, I54M, Q58E, V82A, N83D, I84V, L90M.
1CRT: K101E, K103N, V106I, E138A, E138G, E138K, Y181C; PR: D30N, M46I, M46L, Q58E, V82A.
2ART: K103N, E138A, Y181C, H221Y; PR: M46I, Q58E.
2BRT: M41L, D67N, K70R, V75I, K101E, K101P, K103N, K103S, V106M, V108I, E138A, E138K, E138G, Q151M, Y181C, M184I, M184V, Y188L, G190A, L210W, T215Y, K219E, K219Q, H221Y, P225H, M230I; PR: V32I, M46I, M46L, I54M, Q58E, V82A, N83D, I84V, L90M.
2CRT: K101E, K103N, E138A, E138G, E138K, Y181C; PR: D30N, M46I, M46L, Q58E, V82A.
3BRT: M41L, D67N, K70R, V75I, Q151M, M184I, M184V, L210W, T215Y, K219E, K219Q; PR: –.
4ART: K103N, E138A, Y181C, H221Y; PR: –.
4BRT: V90I, A98G, K101E, K101P, K103N, K103S, V106I, V106M, V108I, E138A, E138K, E138G, V179D, Y181C, Y188L, G190A, H221Y, P225H, M230I; PR: –.
4CRT: K101E, K103N, V106I, E138A, E138K, E138G, Y181C; PR: –.
5ART: K103N, E138A, Y181C, H221Y; PR: –.
5BRT: K101E, K101P, K103N, K103S, V106M, V108I, E138A, E138G, E138K, Y181C, Y188L, G190A, H221Y, P225H, M230I; PR: –.
5CRT: K101E, K103N, E138A, E138G, E138K, Y181C; PR: –.
6ART: K103N, E138A, Y181C, H221Y; PR: M46I, Q58E.
6BRT: –; PR: V32I, M46I, M46L, I54M, Q58E, V82A, N83D, I84V, L90M.
6CRT: –; PR: D30N, M46I, M46L, Q58E, V82A.
Fisher’s Exact test was used to determine if there was a significant difference in the occurrence of resistance mutations between clustered and non-clustered subjects. Significant findings (p<0.05) are highlighted in bold.
创建时间：
2014-02-26
